Alternate aluminium angles for X axis

Hi all, I have been in the process of building a LongMill from scratch. I managed to source 2”x2”x1/4” angles but not 3”x3” for the X axis in my area. However, there is a 4”x4”x1/4” available, I wanted to know if we can still use 2”x2” sandwiched for the X or one 4”x4” by any chance?