I’ve been reading a lot on Bill Pentz’ pages - given:
- It’s my own health I’m protecting here
- His opinion that a few hours in a typical home shop is as bad for you as many months in a commercial, inspected woodworking shop
- You literally can’t see the stuff that’s bad for you, you need an air-quality monitor to tell you that there is danger because you don’t feel anything until it’s far too late, and the damage is done.
- The small-size filters get ripped apart over a short time by the cleaning that you’re supposed to do, to the point where they’re just allowing the dangerous dust through again, but still providing the security blanket of seeing the visible dust get cleaned.
What’s not clear yet is whether a good dust-shoe on a CNC will prevent a lot of the fine dust (<10 micron) that he’s talking about from becoming a problem. It seems to me that this would be similar to the “properly designed shrouds” he talks about on hand-held and smaller machines.
From what I gather, the issue is that the 1000 CFM suction is more or less good enough to capture things escaping with an initial velocity away from the hose at about 50mph. The problem for fine dust collection is that the RPM of the tools are sufficiently high that fine dust can be accelerated away at closer to 100mph… putting a shroud around the tool lets you limit how far the dust can go, and lets it be then gathered up by the suction.
I’m not all the way through his site yet, it’s information-dense and there’s a fair amount of it, but fit does seem to be aimed at the more traditional tools in a shop, not a CNC in particular - of course it does mention the router table, which is one of the worst offenders 
On another note, the air cleaner is useful, but not as an immediate benefit - the filtering action is too slow (even at 12x per hour) to prevent fine dust from getting into your system at the point of creation, but it does circulate the air, and eventually will trap a lot of dust that did make it out of the capture-zone, so very useful to run overall.
A lot of the problems stem from us using systems that were designed on an industrial scale to vent fine particles outside being scaled down to sizes that fit into an 8’ ceiling, and losing a lot of their effectiveness as a result. To add insult to injury they then vent inside the shop because no-one at home has separate exterior venting set up. So fine dust that escapes (and it does because changing the filters suitably often is very expensive and time-consuming) just builds up and up over time.
Still reading the site but it’s fascinating (if a bit depressing) stuff.
To address your point though, the dust shoe that comes with the 2.2kW spindle (my current order for the 4x8 table includes this) is an 80mm (4”) outlet. There’s no real advantage if I immediately adapt that to a 6” since air does not compress at these low pressures, so the effects of a flow restriction remain in place throughout the air path. In fact, even a 6” pipe can only sustain 785 CFM with a standard 3hp collector, or a higher hp one if you’re using a cyclone since that reduces the air flow efficiency through the duct - energy is needed to accelerate the air in a circle) - you really need to go to 7” to get the 1000CFM that is better for fine dust…
I can’t tell what the outlet is on the new ATC spindle, but I expect it’ll be the same 4”. Both would need a redesign in Bill’s world. I guess I have a 3d printer…